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RCTMinds — a specialized subdomain of RSMinds

AI-powered · 16 RCT subtypes · SPIRIT + CONSORT compliant

Design Production-Quality RCTs
From Hypothesis to Synopsis

16 RCT subtypes. 10-section workflow. Deterministic sample-size verifier. Built on SPIRIT 2025, CONSORT 2025, and 16 CONSORT extensions.

No credit card to start7-day money back15,000 Mindful AI Tokens/month
rct.rsminds.com / workflow
01Idea & RCT Subtype
02PICO Framework
03Research Question & FINER
06Sample Size & Power
10Synopsis Generation
+ 5 more sections — see full workflow below
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RCT subtypes covered

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workflow sections — idea to synopsis

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reporting standards integrated platform-wide

0/mo

starts here · 7-day money back

How RCTMinds works

The 10-section workflow

Each section is its own AI-assisted accordion. Outputs flow forward — your PICO informs sample-size; sample-size informs analysis plan; everything assembles into a SPIRIT synopsis.

01

Idea & RCT Subtype

Inputs

Research idea text

AI action

predictRctSubtype

Output

Subtype + category recommendation across 16 designs.

Saves 30–45 min of design-selection deliberation
02

PICO Framework

Inputs

Subtype context

AI action

draftRctQuestion + PICO extraction

Output

P / I / C / O components, ready for question drafting.

Saves 1–2 hours of PICO refinement
03

Research Question & FINER

Inputs

PICO

AI action

auditResearchQuestion

Output

3 question drafts + FINER scoring (Feasibility, Interest, Novelty, Ethics, Relevance).

Saves 2–3 hours vs manual drafting
04

Hypothesis & Variables

Inputs

Question

AI action

draftRctHypothesis + deconstructQuestion

Output

H1 / H0 statements + variables list (IV, DV, mediators, moderators).

Saves ~1 hour and reduces hypothesis-variable mismatches
05

Theory & Framework

Inputs

QuestionVariables

AI action

discoverTheories + generateFramework

Output

3 theory candidates with citations + conceptual framework diagram.

Saves 3–5 hours of literature triangulation
06

Sample Size & Power

Inputs

SubtypeEffect sizeAlphaPower

AI action

calculateSampleSize

Output

N per group + total, plus deterministic verifier (Cohen's d cross-check) with explained assumptions.

Saves 1–2 hours and catches AI hallucination
07

Randomization & Blinding

Inputs

SubtypeN

AI action

suggestRandomization

Output

Scheme + sequence generation + allocation concealment plan.

Saves 1 hour and aligns with CONSORT items 8–10
08

Intervention Protocol

Inputs

PICOSetting

AI action

generateInterventionProtocol

Output

TIDieR-compliant WHO / WHAT / WHEN / HOW / WHERE / WHY description.

Saves 2–4 hours of TIDieR mapping
09

Data Collection & Analysis Plan

Inputs

OutcomesN

AI action

generateAnalysisPlan + generateOutcomeMeasurements

Output

Outcome measures + primary/secondary analyses + statistical approach.

Saves 2–3 hours and matches your subtype assumptions
10

Synopsis Generation

Inputs

All previous sections

AI action

generateSynopsis (parallel SSE)

Output

SPIRIT-compliant synopsis exportable as DOCX, PDF, or Markdown.

Saves a full day of synopsis drafting

Subtype coverage

16 RCT subtypes — all covered

From standard parallel-group trials to N-of-1 designs. Every subtype gets its own design guidance, CONSORT extension mapping, and sample-size formulas.

Basic

4 designs
  • Standard Parallel

    Two arms, randomized, classic comparison.

  • Superiority

    Test that intervention beats control.

  • Equivalence

    Show treatments are clinically indistinguishable.

  • Non-Inferiority

    Demonstrate not worse than standard care.

Factorial

4 designs
  • Factorial 2 × 2

    Two interventions, two levels each.

  • Factorial 2 × 3

    Two interventions, asymmetric levels.

  • Factorial 3 × 3

    Three-by-three full design.

  • Fractional Factorial

    Subset of cells for efficiency.

Crossover

4 designs
  • Two-Period

    AB / BA simple crossover.

  • Three-Period

    Three sequences, balanced.

  • Four-Period

    Higher-order with carryover control.

  • Latin Square

    Each treatment in each position.

Specialized

4 designs
  • Stepped Wedge Cluster

    Sequential rollout across clusters.

  • Basket Trial

    One intervention, multiple diseases.

  • Umbrella Trial

    Multiple interventions, one disease.

  • N-of-1 Trial

    Single-patient multi-period trial.

Compliance

Built on the standards
your reviewers expect

Integrated

SPIRIT 2025

Standard Protocol Items for Clinical Trials

Integrated

CONSORT 2025

Consolidated Standards of Reporting Trials

Integrated

CONSORT Cluster 2012

Cluster trial extension

Integrated

CONSORT Stepped Wedge 2018

Stepped wedge extension

Integrated

CONSORT N-of-1 (CENT) 2015

N-of-1 trials

Integrated

CONSORT Adaptive (ACE) 2020

Adaptive designs

Integrated

CONSORT Equity 2017

Health equity extension

Integrated

CONSORT-AI 2024

AI interventions

Integrated

CONSORT Multi-arm 2019

Multi-arm parallel-group

Integrated

CONSORT Crossover 2019

Randomized crossover

Integrated

CONSORT Factorial 2019

Factorial trials

Integrated

CONSORT Harms 2022

Harms reporting

Integrated

TIDieR 2014

Template for Intervention Description and Replication

Integrated

CASP-RCT

Critical Appraisal Skills Programme

Integrated

Cochrane RoB 2

Risk of Bias assessment

Integrated

GRADE

Grading of Recommendations Assessment

Your protocol is scored against every applicable standard in real time.

Why this matters

Sample size,
but with a second opinion

Other tools

Give you a number. That's it.

If the AI hallucinates — wrong effect-size assumption, dropped allocation ratio, or a formula meant for a parallel design applied to a crossover — you don't know until your ethics committee or supervisor catches it.

RCTMinds

AI suggests. Verifier cross-checks.

A deterministic verifier (Cohen's d for parallel, ICMR-aligned formulas for cluster and crossover) re-computes the number independently. If AI and verifier disagree, we flag it before you commit.

  • Deterministic, not stochastic — same inputs, same answer.
  • ICMR-aligned formulas for Indian regulatory pathways.
  • Disagreement flagged with explainer for both methods.
section 6 / sample size & power · superiority parallel-group

AI estimate

N = 160

per group · α 0.05 · power 0.80 · d 0.40

Verifier (Cohen's d)

N = 158

deterministic · same inputs

Agreement

98.7%

Within 2% — safe to proceed

Plans

Simple pricing

7-day money-back guarantee

Access 1m

299/ 30 days

15,000 Mindful AI Tokens

  • All 16 RCT subtypes
  • 10-section workflow
  • SPIRIT + CONSORT exports
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FAQ

Frequently asked questions

Common questions from researchers, supervisors, and IEC reviewers.

Can I use this for ICMR-funded research?

Yes. Sample-size formulas align with ICMR norms; reporting standards include SPIRIT 2025 which ICMR accepts. The platform also supports the CONSORT extensions ICMR reviewers commonly reference.

Is the sample-size calculation accurate?

AI proposes, a deterministic verifier cross-checks. Cohen's d for parallel designs; ICMR-aligned formulas for cluster, crossover, and stepped-wedge. Disagreements are flagged with explainers for both methods before you commit to a number.

Will my ethics committee accept the synopsis?

Output is SPIRIT 2025 compliant. Indian and international ethics committees recognise the format. You retain full editorial control — every line is editable before export.

Can I edit the AI output?

Every section is editable. The AI drafts; you decide what ships. Edits propagate downstream — change your PICO and the question, hypothesis, and sample size all re-evaluate.

What if I run out of Mindful Tokens mid-month?

Top up any time with Boost (₹149), Lab (₹349), or Project (₹699) packs. Top-up tokens never expire while you remain subscribed.

Do you store my research data?

Your study details stay in your account. We never train models on your data. PII is redacted before any AI call. Exports are yours to keep even after subscription ends.

Can I import an existing protocol?

Yes. Paste any synopsis text and the tool extracts PICO, hypothesis, and sample-size context to continue from where you left off — no re-typing.

What export formats are supported?

DOCX, PDF, and Markdown. All exports preserve SPIRIT structure and formatting for direct ethics-committee submission.

Is there a free trial?

7-day money-back guarantee on any plan. Free reference guides at /flow-minds/ require no signup if you just want to browse the methodology content.

Can I cancel anytime?

Yes — cancel from Settings. Access continues to the end of the paid period. No questions asked, no retention calls.

Start your RCT design in 5 minutes.

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